Velma-Alma also defeats the Ringling boys basketball team.
In Enid, the host Northern Oklahoma Enid Jets built a 12-point lead after one quarter.
Murray State responded in the second quarter, quadrupling its scoring output from the opening period.
Bailee Eldred paced MSC with eight points, but NOC defeated Murray State 57-37 on Tuesday.
Hannah Howard converted a 3-pointer in the second quarter.
Dossou Ndiaye and Sarah Garvie scored 16 points apiece to pace NOC. Garvie had two 3-pointers in the first and third quarters. Ndiaye scored four points apiece in the first and third quarters — and eight in the second quarter — all via two-point field goals.
Eldred, a sophomore guard and took 10 shots to record her eight points. She was 0 of 2 from three-point distance. The Class of 2015 Sulphur High School alumna also contributed three rebounds, a block and a steal to accompany four turnovers.
Howard, a Class of 2016 Lone Grove High School alumna, finished with five points on 2 of 10 shooting. She shot 1 of 6 from behind the arc. She added two rebounds and two blocked shots to accompany a turnover.
Carolyne Lawley, a Class of 2015 Tishomingo High School alumna, scored her two points in the opening quarter. She and Eldred had one field goal apiece in that first period.
Lawley shot 1 of 4, grabbing five rebounds — one offensive — and dishing out an assist against one turnover.
MSC (9-11) committed 18 turnovers.
MSC 4 17 6 10 — 37
NOC 16 18 17 6 — 57
MSC: Bailee Eldred 8, Amaka Nwakamma 6, Hannah Howard 5, Oumy Ndoye 4, Charlea Leonard 4, Natalia Pushkareva 4, Aaliyah Endsley 2, Erin Estep 2.
MSC: 3 (Amaka 2, Howard)
NOC 78, MSC 67
In the second game of the doubleheader, Enis Memic scored a team-high 20 points and grabbed 14 rebounds — nine offensive.
MSC didn't have another double-digit scorer in a 78-67 loss Tuesday.
Kiantae Wilson scored nine off the bench via three 3-pointers, hitting half of MSC's six. The Aggies shot 6 of 25 (24 percent) from behind the arc.
Joao Avena-Felix and Rodney Hinkle scored eight points apiece.
Avena-Felix also had a team-high four assists, while Wilson paced MSC with three of the team's nine steals.
Velma-Alma 38, Ringling 32
In Velma on Tuesday, in the Blue Devils' regular-season finale, the Velma-Alma Comets earned a 38-32 win.
The teams played to an 11-11 tie through one quarter. Velma-Alma led 22-20 at half — then pulled away in the third quarter, scoring 10 points to Ringling's five.
Caige Calvert scored nine points while Zaine Sanner and Zack Cargile scored eight apiece.
Dewyatt Cox contributed five points while Travis Wade and Matthew Paul hit one free throw apiece.